KRAS inhibitors-Market opportunity, Epidemiology & Market Forecast, Pipeline and Competitive Analysis, 2020-2030

Description

Kirsten rat sarcoma viral oncogene homolog (KRAS) mutation may directly influence medical decisions in patients with carcinomas as demonstrated by the recent research. Despite its discovery over three decades ago, it’s remained elusive as a drug target, although several downstream mediators are effectively drugged. KRAS itself is described collectively of the master switches for cancer and is especially associated as a driver for Colorectal Carcinoma (CRC), Non-small Lung cancer (NSCLC), and carcinoma.

While KRAS mutations are present in up to 25% of cancers, the oncogenic variants have different prevalence rates in numerous cancers. As per the American Cancer Society, around 200,000 patients are diagnosed every year with lung adenocarcinomas. That puts the KRAS-G12C population within the USA at 14,000–28,000 patients annually. within the case of KRAS-G12C-positive colorectal cancer (CRC), closer to 3000 patients are diagnosed every year.

Amgen certainly has a headstart over its potential opponents, and it is unlikely that a competitor would have the option to sling in front of an expedited development program for AMG 510. Mirati Therapeutics, another competitor, entered the clinic with the KRAS-G12C inhibitor MRTX849, followed by other companies. While there is already a lot of excitement about the new drug, the number of patients who have been treated with it is relatively small.

This KRAS report covers the KRAS market opportunity providing key competitive analysis, 37 companies with pipeline drug profiles, clinical trials, upcoming events, other Developments (Collaborations Details, Funding, etc.), Epidemiology forecast of Cancers with KRAS mutation and % of mutation frequency, licensing and deals, as well as presenting market forecast from 2019 to 2030.

Key Takeaways from the Report

• Indication Prioritization: KRAS Mutation patterns in cancers
• KRAS Mutated Cancers Epidemiology Forecast from 2019-2030
• Business Transactions & Strategies: Key collaborations and deal values
• Pipeline Development: Product Profiles, Clinical Trials & Results
• Market Forecast of KRAS Inhibitors from 2019-2030
• Recent & Upcoming events